Description
CJC-1295 + Ipamorelin
CJC-1295 + Ipamorelin is a research-grade dual-peptide formulation combining two compounds that work through different pathways to stimulate growth hormone (GH) release. Both have been studied in preclinical and early clinical research for their complementary effects on the body’s GH system.
CJC-1295
- A synthetic peptide that mimics the body’s natural growth hormone-releasing hormone (GHRH), engineered to last significantly longer in the body than its natural counterpart
- Signals the pituitary gland to produce and release GH and IGF-1 in a sustained, natural-feeling pattern
- Research has documented a half-life of 5.8–8.1 days, with IGF-1 levels remaining elevated for up to 28 days after repeated dosing (Teichman et al., 2006)
Ipamorelin
- A short synthetic peptide that selectively triggers GH release from the pituitary gland by mimicking ghrelin, a naturally occurring hormone
- Notably selective — research shows it does not stimulate stress hormones such as cortisol, even at very high doses, setting it apart from similar compounds (Raun et al., 1998)
- GH release is driven through well-characterised intracellular signalling pathways (Sinha et al., 2020)
Combined Research Utility
Because the two peptides work through separate pathways, researchers can study the effects of stimulating GH through both routes simultaneously within a single experimental protocol. GH release patterns remain natural and pulsatile under this combined stimulation (Ionescu & Frohman, 2006).
For research use only. Not intended for use in humans or animals.
References
Ionescu, M., & Frohman, L. A. (2006). https://pubmed.ncbi.nlm.nih.gov/17018654/
Raun, K., Hansen, B. S., Johansen, N. L., Thøgersen, H., Madsen, K., Ankersen, M., & Christiansen, P. H. (1998). https://pubmed.ncbi.nlm.nih.gov/9849822/
Sinha, D. K., Balasubramanian, A., Tatem, A. J., Rivera-Mirabal, J., Yu, J., Kovac, J., Pastuszak, A. W., & Lipshultz, L. I. (2020). https://pmc.ncbi.nlm.nih.gov/articles/PMC7108996/
Teichman, S. L., Neale, A., Lawrence, B., Gagnon, C., Castaigne, J.-P., & Frohman, L. A. (2006). https://pubmed.ncbi.nlm.nih.gov/16352683/















